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For some xenobiotics, the toxicity may involve biliary and oval cells (Figure 9), produce cholestasis, or be associated with vascular occlusive changes and granulomatous inflammation

Special attention is given to the translational potential of microbiome-based approaches, including dietary modification, psychobiotics, and FMT, to prevent or mitigate CNS disorders

The same teams extended observations to colitis, induced hepatitis and experimental digestive fistulas